Endometrial Cancer: Introduction FeedbackA general introduction to Endometrial Cancer.Source: NHS Choices, 21 Nov 2012
Cancer of the womb (uterus) is a common cancer that affects the female reproductive system. It is also called uterine cancer and endometrial cancer.
Abnormal vaginal bleeding is the most common symptom of womb cancer.
If you have been through the menopause, any vaginal bleeding is considered to be abnormal. If you have not yet been through the menopause, unusual bleeding may include bleeding between your periods.
You should see you GP as soon as possible if you experience any unusual vaginal bleeding. While it is unlikely that it is caused by womb cancer, it is best to be sure.
Your GP will examine you and ask about your symptoms. If they suspect you may have a serious problem or if they are unsure about a diagnosis, they will refer you to a specialist for further tests.
Types of womb cancer
The vast majority of womb cancers begin in the cells that make up the lining of the womb (called the endometrium), which is why cancer of the womb is often called endometrial cancer.
In rare cases, womb cancer can start in the muscles surrounding the womb. This type of cancer is called uterine sarcoma and may be treated in a different way to endometrial cancer.
This article uses the term womb cancer and mostly includes information about endometrial cancer. See the Cancer Research UK website for more information about soft tissue sarcomas.
Why does womb cancer happen?
It is not clear exactly what causes womb cancer, but certain things can increase your risk of developing the condition.
A hormone imbalance is one of the most important risks for womb cancer. Specifically, your risk is increased if you have high levels of a hormone called oestrogen in your body.
A number of things can cause this hormone imbalance, including the menopause, obesity, diabetes and hormone replacement therapy (HRT). There is also a small increase in the risk of womb cancer with long-term use of the breast cancer drug tamoxifen.
It is not always possible to prevent womb cancer, but some things are thought to reduce your risk. This includes maintaining a healthy weight and the long-term use of some types of contraception.
How is womb cancer treated?
The most common treatment for womb cancer is the surgical removal of the womb (hysterectomy). A hysterectomy can cure womb cancer in its early stages, but you will no longer be able to get pregnant. Surgery for womb cancer is also likely to include the removal of the ovaries and fallopian tubes.
A type of hormone therapy may be used if you are yet to go through the menopause and would still like to have children.
Even if your cancer is advanced and the chances of a cure are small, treatment can still help to relieve symptoms and prolong your life.
Read more about treating womb cancer.
Living with womb cancer
Living with cancer is challenging and womb cancer can affect your life in specific ways.
For example, your sex life may be affected if you have a hysterectomy. You may find it physically more difficult to have sex and you may have a reduced sex drive.
You may find it beneficial to talk to other people about your condition, including family members, your partner or other people with womb cancer.
Read more about living with womb cancer.
Endometrial Cancer: Commissioning FeedbackThe most relevant search results for Endometrial Cancer from producers of commissioning advice.
Information for the public
Endometrial Cancer: Information for the public FeedbackThe most relevant search results for Endometrial Cancer, from Department of Health accredited producers of patient information.
Endometrial Cancer: Ongoing Research FeedbackThe most relevant search results for Endometrial Cancer, from research trials.
Study of Genes and the Environment in Patients With Endometrial Cancer in the East Anglia, Oxford, Trent, or West Midlands Regions of the United KingdomUK Clinical Trials Gateway, 22 September 2008
Study Comparing AEZS-108/ZoptEC (Zoptarelin Doxorubicin in Endometrial Cancer) to Doxorubicin as a Second Line Therapy of Endometrial CancerUK Clinical Trials Gateway, 09 January 2013
- UK Clinical Trials Gateway, 22 May 2012
- UK Clinical Trials Gateway, 23 April 2014
- UK Clinical Trials Gateway, 17 January 2014
Diagnostic Accuracy of MRI, DWI MRI, FDG-PET/CT and FEC PET/CT in the Detection of Lymph Node Metastases in Surgically Staged Endometrial and Cervical CarcinomaUK Clinical Trials Gateway, 31 January 2013
- UK Clinical Trials Gateway, 20 April 2012
Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment SchedulesUK Clinical Trials Gateway, 21 October 2010
Hyperbaric Oxygen Therapy in Treating Long-Term Gastrointestinal Adverse Effects Caused by Radiation Therapy in Patients With Pelvic CancerUK Clinical Trials Gateway, 13 March 2010
Study of Physical and Psychosocial Rehabilitation Needs of Patients After Diagnosis and Treatment of Upper Gastrointestinal Cancer or Gynecological CancerUK Clinical Trials Gateway, 06 October 2010
Endometrial Cancer: Evidence Uncertainty FeedbackThe most relevant search results for Endometrial Cancer, highlighting areas where further research is needed.
- UK Database of Uncertainties about the Effects of Treatments, 06 June 2014
- UK Database of Uncertainties about the Effects of Treatments, 14 March 2012
- UK Database of Uncertainties about the Effects of Treatments, 17 February 2014
- UK Database of Uncertainties about the Effects of Treatments, 28 April 2011
- UK Database of Uncertainties about the Effects of Treatments, 20 September 2013
- UK Database of Uncertainties about the Effects of Treatments, 19 September 2012
- UK Database of Uncertainties about the Effects of Treatments, 18 April 2013
- UK Database of Uncertainties about the Effects of Treatments, 14 November 2011
Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndromeUK Database of Uncertainties about the Effects of Treatments, 03 April 2008
- UK Database of Uncertainties about the Effects of Treatments, 28 August 2012
Endometrial Cancer: Medicines FeedbackAppropriate medicines information for Endometrial Cancer supplied by Datapharm, a leading source of trusted, credible information about medicines.
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...colorectal, and endometrial cancers: a systematic review. Cancer Epidemiology...of other cancers and the POP...the risk of endometrial cancer. Effect...of other cancers and indeed...the risk of endometrial cancer'[NICE...
Clinical Knowledge Summaries, 01 June 2012
...infertility with ovarian cancer risk. Am J Epidemiol 2007...contraceptives and the risk of all cancers combined and site-specific cancers in Shanghai. Cancer Causes Control 2009; 20...Oral contraceptives and endometrial cancer. Obstet Gynecol...
Faculty of Sexual and Reproductive Healthcare, 10 August 2012
...prevention of adverse endometrial effects, eg hyperplasia and cancer. The regimen...to endometrial cancer, 12-14 days...75 and 100 the endometrial safety of added...Rare Breast cancer Frequency not known Endometrial cancer Immune...
electronic Medicines Compendium, 21 May 2014 - Publisher: electronic Medicines Compendium (eMC), Datapharm Communications Ltd - Publication type: Summary of Product Characteristics
...suspected breast cancer Known or suspected...tumours (eg endometrial cancer) or pre...Uncommon Breast cancer, fibroadenoma...not known Endometrial cancer Immune...increase the risk of endometrial hyperplasia and cancer. The addition...
electronic Medicines Compendium, 30 April 2013 - Publisher: electronic Medicines Compendium (eMC), Datapharm Communications Ltd - Publication type: Summary of Product Characteristics
...suspected breast cancer Known or suspected...malignant tumours (eg endometrial cancer) or pre...Breast neoplasms, Endometrial cancer Immune System...increase the risk of endometrial hyperplasia and cancer. The addition of...
electronic Medicines Compendium, 02 April 2012 - Publisher: electronic Medicines Compendium (eMC), Datapharm Communications Ltd - Publication type: Summary of Product Characteristics
...past or suspected cancer of the breast ...malignant tumours (eg endometrial cancer) • Undiagnosed...increase in risk of breast cancer Endometrial cancer risk Postmenopausal...with a uterus The endometrial cancer risk is about...
electronic Medicines Compendium, 26 October 2011 - Publisher: electronic Medicines Compendium (eMC), Datapharm Communications Ltd - Publication type: Summary of Product Characteristics
...discontinuation. CERVICAL CANCER (awaiting treatment...woman sterile. ENDOMETRIAL AND OVARIAN CANCER...surgery. CERVICAL CANCER (awaiting treatment...woman sterile. ENDOMETRIAL AND OVARIAN CANCER...Family history of cancer d) Carriers of...disease for 5 years ENDOMETRIAL CANCER OVARIAN CANCER...
Faculty of Sexual and Reproductive Healthcare, 19 May 2010
...past or suspected breast cancer • Known or suspected estrogen...dependent malignant tumuours (eg endometrial cancer) • Undiagnosed genital bleeding • Untreated endometrial hyperplasia • Previous...was associated with breast cancers that were slightly larger...radiological detection of breast cancer. Venous thrombo-embolism...
electronic Medicines Compendium, 22 June 2009 - Publisher: electronic Medicines Compendium (eMC), Datapharm Communications Ltd - Publication type: Summary of Product Characteristics
...colorectal, and endometrial cancers: a systematic review. Cancer Epidemiology...with breast cancer (for example...Cervical ectropion Endometrial or ovarian...with breast cancer (for example...Cervical ectropion Endometrial or ovarian cancer...
Clinical Knowledge Summaries, 01 June 2012
...include: Unwanted pregnancy. Cervical cancer. Infertility. Sexually transmitted...return of normal fertility). Risk of cancer: There is no overall increased risk of cancer with COCs. COCs reduce the risk of ovarian...
Clinical Knowledge Summaries, 01 June 2012
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