Evidence-based recommendations on adalimumab (Humira), etanercept (Enbrel), infliximab (Remicade, Remsima, Inflectra), certolizumab pegol (Cimzia), golimumab (Simponi), tocilizumab (RoActemra) and abatacept (Orencia). These drugs are for adults with severe rheumatoid arthritis who have tried conventional DMARDs only but they have not worked.
The recommendations also apply to biosimilar products of the technologies that have a marketing authorisation allowing the use of the biosimilar for the same indication.
We reviewed the evidence in September 2019 and we are updating the guidance for people with moderate disease.
There is a simple discount patient access scheme for abatacept. Contact UKCommercialEnquiries@bms.com for details.
There is a complex patient access scheme for certolizumab pegol. Contact UCBCares.UK@ucb.com for details.
There is a complex patient access scheme for golimumab. Contact email@example.com for details.
There is a simple discount patient access scheme for tocilizumab. Contact Welwyn.firstname.lastname@example.org for details.
This guidance replaces NICE technology appraisal guidance on:
It partially updates golimumab for the treatment of rheumatoid arthritis after the failure of previous disease-modifying anti-rheumatic drugs (TA225) and tocilizumab for the treatment of rheumatoid arthritis (TA247).