NICE summary of Cochrane review conclusions
Bariatric surgery for non-alcoholic steatohepatitis in obese patients is not supported by sufficient good quality evidence. Consideration could be given to using it only within the context of a research or audit project. Reducing or stopping bariatric surgery for non-alcoholic steatohepatitis in obese patients is likely to improve quality of patient care and result in productivity savings by avoiding unnecessary operations.
The ‘Implications for practice’ section of the Cochrane review stated:
’The lack of randomised clinical trials to demonstrate the beneficial or harmful effects of bariatric surgery procedures for treatment of non-alcoholic steatohepatitis (NASH) could not enable us to reach any scientifically sustained conclusion. Despite positive results observed in cohort studies, due to their high risk of bias and the potential risk for worsening in fibrosis scores, bariatric surgery needs to be assessed in randomised clinical trials.’