In this paper we feature four areas of women’s reproductive and gynaecological health. This has been informed by the academic and grey literature, and by conversations with a number of expert interviews. Its purpose is to shine a light upon the implications for work, and how this might be managed to reduce the risk of women facing additional challenges in work merely due to being a woman. In looking at endometriosis, infertility, pregnancy and health, and menopause, we hope not only to directly identify ways to improve working life for women, but also more generally to push these issues into the spotlight, and get more employers, policy makers, health professionals and others talking with everyday working women to understand and help to solve challenges at work relating to female biology.