This document provides the dataset for the histological reporting of primary cutaneous Merkel cell carcinoma (primary cutaneous high grade neuroendocrine carcinoma) and associated regional lymph nodes. Merkel cell carcinoma can very occasionally arise in extracutaneous locations. The proven value of this dataset in that situation must currently be regarded as uncertain. It results from a new international staging system for Merkel cell carcinoma within the spectrum of non-melanoma skin cancer.
The meticulous diagnosis and reporting of Merkel cell carcinoma is important because histological parameters play a significant role in defining patient treatment. Similarly, recording of pathological parameters in the dataset has direct implications for the staging and prognosis of individual patients.