Abstract
Whilst there are no specific surgical complications of salt-wasting alkaloses (SWA), these
patients may require surgical procedures like anyone else. Hypokalaemia and
hypomagnesaemia are common in patients with SWA. There are perioperative risks
associated with hypokalaemia, which may be potentiated by low magnesium levels. These
include arrhythmia, weakness, tetany, ileus, metabolic alkalosis and confusion. ECG
changes seen in hypokalaemia included increased P-wave amplitude, prolonged PR
interval, apparent QT interval prolongation, reduction in T-wave amplitude, T-wave
inversion, ST segment depression and U-waves. However the current perioperative
approach in patients with SWA is inconsistent, and patients may equally be denied surgery
on the basis of chronic and stable metabolic derangement. The purpose of this guideline is to reduce this variation and therefore improve practice. The US National Guideline Clearinghouse does not contain existing guidelines on this subject.