Dataset for histopathological reporting of ocular retinoblastoma

Royal College of Pathologists - RCPATH
Royal College of Pathologists
Publication date:
01 January 2018


This proposal for the reporting of ocular retinoblastoma should be implemented for the following reasons:

  • staging of the disease
  • the determination of whether adjuvant treatment (chemotherapy or radiotherapy) is required, based on the histological identification of ‘high-risk factors’ (HRFs) for metastasis. These HRFs include involvement of the anterior segment structures, choroid, the sclera, extraocular spread, retrolaminar optic nerve involvement and involvement of the optic nerve surgical resection margin
  • to provide prognostic information
  • to provide accurate data for cancer registration
  • potentially to assist in selecting patients for future trials of adjuvant therapy
  • to provide data for clinical audit and effectiveness
  • to provide a database for research.

This document replaces the 2nd edition of 'Dataset for ocular retinoblastoma histopathology reports', published in 2010.