Postoperative opioids, endocrine changes, and immunosuppression

Source:
International Association for the Study of Pain
Publisher:
International Association for the Study of Pain (IASP)
Publication date:
01 March 2018

Abstract

This update will focus on a different subset of effects associated with the use of opioid analgesics in the acute postoperative setting; these are endocrine changes and immunosuppression. This clinical update will discuss the evidence behind the role of opioids in contributing to each of these phenomena in the postoperative setting, discuss their clinical relevance, and summarize the recent data on approaches that could be considered when treating pain in patients after surgery.