This report details the findings of a desktop exercise involving public health and security experts from 24 EU member states.  The main purpose of the exercise was to bring together experts from public health and civil protection/security sectors to consider the coordinated crisis response to cross-border threats facing European Union (EU) Member States, European Economic Area (EEA) and other countries, EU institutions and agencies as well as international organisations caused by a hybrid threat. The scenario for the exercise focussed on a fictitious terrorist organisation who caused an outbreak of a communicable disease following a deliberate release and undertook concurrent cyber-attacks on critical infastures including hospitals.