Paracetamol versus placebo for knee and hip osteoarthritis

Source:
Cochrane Database of Systematic Reviews
Publisher:
Cochrane Database of Systematic Reviews
Publication date:
24 February 2019

Abstract

Review of 10 RCTs (vs.placebo;n=3541) found high-quality evidence confirms paracetamol provides only minimal improvements in pain /function for people with hip/knee osteoarthritis, with no increased risk of ADRs overall. It calls for guideline recommendations to be reconsidered.