Medicines Evidence Commentary : Irritable bowel syndrome: effect of antidepressants and psychological interventions

National Institute for Health and Care Excellence - NICE
National Institute for Health and Care Excellence (NICE)
Publication date:
25 March 2019


A systematic review and meta-analysis found that antidepressants and psychological therapies are effective for reducing symptoms in adults with irritable bowel syndrome (IBS). Despite some limitations with the quality of the evidence, the findings support NICE recommendations on the management of IBS in adults. There is national variation relating to accessibility to psychological therapies for IBS, which is dependent on local commissioning.

This link will take you to the medicines evidence commentary featured in the NICE Medicines Awareness Weekly. Medicines evidence commentaries help contextualise important new evidence, highlighting areas that could signal a change in clinical practice. It does not constitute formal NICE guidance.