Revised SPC: Ancotil (flucytosine) 2.5g/250ml Solution for Infusion

Source:
electronic Medicines Compendium - eMC
Publisher:
electronic Medicines compendium
Publication date:
26 June 2019

Abstract

Sections 4.2 and 4.4 now advise there is insufficient evidence to support use in paediatric patients. Section 4.4 now also advises flucytosine has a narrow therapeutic window and there is a risk of its potential toxicity at high systemic concentrations.