||Uncertainties identified from carers' questions
||James Lind Alliance Palliative and end of life care Priority Setting Partnership
|Why is there uncertainty?
||Reliable up-to-date systematic reviews have revealed important continuing uncertainties about treatment effects
This uncertainty was identified from two patient's, three professionals, three carer's and one bereaved carer's question.
This is an indicative uncertainty and the following submissions were merged to form this one:
More information about the extreme side of end of a life should be available to help plan better
What is happening when someone develops terminal restlessness - what do we understand about it now and what more can we discover (that will be helpful)? What is the most effective way to use sedation (eg during terminal restlessness) - in order to get the balance right between not giving too much but at the same time giving enough to ease distress.
References to reliable up-to-date systematic reviews:
Beller EM, van Driel ML, McGregor L, Truong S, Mitchell G. Palliative pharmacological sedation for terminally ill adults. Cochrane Database of Systematic Reviews 2015, Issue 1. Art. No.: CD010206. DOI: 10.1002/14651858.CD010206.pub2.
Candy B, Jackson KC, Jones L, Leurent B, Tookman A, King M. Drug therapy for delirium in terminally ill adult patients. Cochrane Database of Systematic Reviews 2012, Issue 11. Art. No.: CD004770. DOI: 10.1002/14651858.CD004770.pub2.
|What is needed?
|Systematic reviews that need updating or extending
|Systematic reviews in preparation
|Ongoing controlled trials
|Which health conditions?
||Service delivery, organisation and staffing | Palliative and end of life care
|What is person's age?
|Which types of treatments?
Health related quality of life, good death, Change in symptoms or change in management of symptoms, adverse effects or complications
||Publication date:08 Sep 2015
|Last reviewed date:08 Sep 2016
||Publication Type:Known Uncertainty
|The DUETs team endeavours to ensure that information is correct at the time of data entry