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Cochrane Database of Systematic Reviews (Remove filter)

Published by Cochrane Database of Systematic Reviews, 10 December 2020

This review (7 trials; n=7,817) found IV administration of oxytocin is more effective than intramuscular administration in preventing postpartum haemorrhage during vaginal birth, with a comparable...

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Published by Cochrane Database of Systematic Reviews, 17 December 2020

This review of 19 RCTs (n=2959) found there is insufficient evidence that corrector monotherapy has clinically important effects in pwCF with F508del/F508del. Further RCTs are required in children...

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Published by Cochrane Database of Systematic Reviews, 14 December 2020

This review of 34 studies (n=1960) found the available evidence does not support the superiority of any anticoagulant to another. Further studies are needed to identify patient populations in which...

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Cochrane Database of Systematic Reviews (Remove filter)

Published by Cochrane Database of Systematic Reviews, 08 February 2021

Review (27 RCTs; n=2319) found melatonin given as premedication probably reduces preoperative anxiety in adults vs placebo, with a smaller effect on postoperative anxiety. There was little or no...

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Published by Cochrane Database of Systematic Reviews, 25 December 2020

Evidence from updated review (27 studies, n=11,272 women and 11,925 neonates) supports continued use of single course of antenatal corticosteroids to accelerate foetal lung maturation. Treatment...

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Published by Cochrane Database of Systematic Reviews, 08 December 2020

Review (6 studies, n=5542) found mepolizumab and benralizumab probably reduce the rate of moderate and severe exacerbations in the highly selected group of people who have both COPD and higher levels...

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Published by Cochrane Database of Systematic Reviews, 21 December 2020

This updated review (13 RCTs; n=1132) found no conclusive evidence that use of metformin before or during IVF/ICSI treatment in women with PCOS improves live birth rates. It may reduce incidence of...

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Published by Cochrane Database of Systematic Reviews, 20 February 2021

Review (one RCT; n=47) found limited, very low-quality evidence that iloprost ± recombinant tissue plasminogen activator, in combination with buflomedil, may reduce need for amputation in severe...

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Published by Cochrane Database of Systematic Reviews, 18 February 2021

This updated review (32 RCTs [6 new]; n=15,678) found LMWH reduce, and direct factor Xa inhibitors may reduce, incidence of symptomatic VTE; both likely increase risk of major bleeding. Evidence for...

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Published by Cochrane Database of Systematic Reviews, 12 December 2020

Updated review found sodium reduction resulted in mean arterial pressure (MAP) decrease of about 0.4 mmHg in white subjects with normal BP and a MAP decrease of about 4 mmHg in white subjects with...

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