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electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 16 April 2020

SPC now includes information on dosing, monitoring and the safety profile in patients with severe renal impairment. Details of a dedicated study evaluating pharmacokinetics in patients with advanced...

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Prescribing and Technical Information (Remove filter)

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electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 08 April 2020

The SPC now lists acute pancreatitis as an uncommon adverse event, and notes that diabetic ketoacidosis has been reported in insulin-dependent patients whom had rapid discontinuation or dose...

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Prescribing and Technical Information (Remove filter)

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electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 08 April 2020

SPC notes capsules should be taken 30 min before or one hour after meals (previously stated with, or immediately after, meals). New information added to the ‘Warnings related to interactions’ section...

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SPS comment

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Prescribing and Technical Information (Remove filter)

Source:

electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 08 April 2020

Information on a randomised, double-blind study comparing caspofungin to amphotericin B deoxycholate in neonates and infants <3 months with invasive candidiasis has been added to the SPC. Based on...

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Prescribing and Technical Information (Remove filter)

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electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 08 April 2020

Additions to the warnings and precautions section include a recommendation to monitor thyroid function in neonates; caution when using with barium sulfate, and an updated warning regarding sodium...

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Prescribing and Technical Information (Remove filter)

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electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 08 April 2020

The SPC now notes that the solution for infusion has a pH of 6.2 – 6.8 and an osmolality of 324 - 396 mOsmol/kg. Further information from PV Study 2 (comparison with mycophenolate mofetil in patients...

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Prescribing and Technical Information (Remove filter)

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electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 08 April 2020

The SPC now notes that the solution for injection has a pH of 5.2 – 5.8 and an osmolality of 300 - 400 mOsmol/kg.

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Prescribing and Technical Information (Remove filter)

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electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 08 April 2020

Erythema multiforme has been added as a new adverse drug reaction.

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Prescribing and Technical Information (Remove filter)

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electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 07 April 2020

SPC now clarifies that no dose reductions of pembrolizumab are recommended, and it should be withheld or discontinued to manage adverse reactions according to specific detail in the SPC.

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SPS comment

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Prescribing and Technical Information (Remove filter)

Source:

electronic Medicines Compendium - eMC (Remove filter)

Published by electronic Medicines compendium, 21 April 2020

SPC now includes detail for treatment of severe acute exacerbations of myasthenia gravis as a new licensed indication.

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SPS comment

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Prescribing and Technical Information (Remove filter)