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Results for all evidence | Drugs and Technologies | electronic Medicines Compendium - eMC | Medicines Current Awareness 41 - 50 of 187 sorted by relevance / date

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Revised SPC: Atriance (nelarabine) 5 mg/ml solution for infusion

Remove: electronic Medicines Compendium - eMC source - 28 November 2019 - Publisher: electronic Medicines compendium

Additional contraception information has been added to SPC to advise that men with partners who are pregnant or could become pregnant should use condoms during treatment with nelarabine.

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Revised SPC: Primene 10% solution for infusion

Remove: electronic Medicines Compendium - eMC source - 28 November 2019 - Publisher: electronic Medicines compendium

SPC updated to advise that when used in neonates and children below 2 years of age, the solution (in bottles and administration sets) should be protected from light exposure until administration is...

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Revised SPC: Neulasta (pegfilgrastim)

Remove: electronic Medicines Compendium - eMC source - 29 November 2019 - Publisher: electronic Medicines compendium

SPC contains warnings on Stevens-Johnson syndrome, a rare but life-threatening or fatal adverse event. Treatment should be discontinued in affected patients.

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Revised SPCs: Ofev (nintedanib) 100 and 150 mg soft capsules

Remove: electronic Medicines Compendium - eMC source - 22 January 2020 - Publisher: electronic Medicines compendium

Headache (frequency common) and alopecia (frequency uncommon) have been added as adverse effects to the SPC.

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Revised SPCs: Giotrif (afatinib) film-coated tablets- all strengths

Remove: electronic Medicines Compendium - eMC source - 22 January 2020 - Publisher: electronic Medicines compendium

SPCs updated to warn GI perforation, including fatalities, has been reported during treatment in 0.2% patients in RCTs, which in majority of cases, was linked to other known risk factors e.g.

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Revised SPC: Fluarix Tetra suspension for injection (influenza vaccine-split virion, inactivated) in pre-filled syringe

Remove: electronic Medicines Compendium - eMC source - 22 January 2020 - Publisher: electronic Medicines compendium

SPC has been updated to advise that Fluarix Tetra can be concomitantly administered with adjuvanted herpes zoster vaccine (Shingrix).

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Revised SPCs: Vargatef (nintedanib) 100 and 150 mg soft capsules

Remove: electronic Medicines Compendium - eMC source - 22 January 2020 - Publisher: electronic Medicines compendium

Headache (frequency common) and alopecia (frequency very common) have been added as adverse effects to the SPC.

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Revised SPC: Edurant (rilpivirine) tablets

Remove: electronic Medicines Compendium - eMC source - 21 January 2020 - Publisher: electronic Medicines compendium

SPC now highlights that a moderate amount of data on pregnant women (between 300-1000 pregnancy outcomes) indicate no malformative or feto/neonatal toxicity of rilpivirine.

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Revised SPC: Metoclopramide Injection 5mg/ml

Remove: electronic Medicines Compendium - eMC source - 20 January 2020 - Publisher: electronic Medicines compendium

The SPC has been updated to include breastfeeding and use within 3-4 days of operations such as pyloroplasty or gut anastomosis as new contraindications. Also noted to have moderate influence on...

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Revised SPC: Tasigna (nilotinib) Hard Capsules (all strengths)

Remove: electronic Medicines Compendium - eMC source - 09 December 2019 - Publisher: electronic Medicines compendium

Sections 4.4 and 4.8 have been updated to advise that in the paediatric population, growth retardation has been documented in patients treated with nilotinib. Close monitoring of growth in paediatric...

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