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Results for all evidence | Drugs and Technologies | Medicines Current Awareness | electronic Medicines Compendium - eMC 31 - 40 of 260 sorted by relevance / date

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Revised SPC: Celebrex (celecoxib) 100mg capsule

Remove: electronic Medicines Compendium - eMC source - 13 January 2020 - Publisher: electronic Medicines compendium

Section 4.4 now includes concomitant use of antiplatelet drugs as a risk factor for increased incidence for upper and lower gastrointestinal complications.

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Revised SPC: Remicade (infliximab) 100mg powder for concentrate for solution for infusion

Remove: electronic Medicines Compendium - eMC source - 28 October 2019 - Publisher: electronic Medicines compendium

‘Cerebrovascular accidents in close temporal association with infusion’ has been added to SPC as adverse effect of unknown frequency.

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Revised SPC: Imfinzi (durvalumab) infusion

Remove: electronic Medicines Compendium - eMC source - 03 December 2019 - Publisher: electronic Medicines compendium

SPC updated to reflect that myasthenia gravis has been reported as a rare adverse effect of treatment. If there are signs of muscular weakness or respiratory insufficiency, durvalumab should be...

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Revised SPCs: Keytruda (pembrolizumab) powder for concentrate for solution for infusion – all strengths

Remove: electronic Medicines Compendium - eMC source - 25 November 2019 - Publisher: electronic Medicines compendium

The following new indication has been added: pembrolizumab, as monotherapy or in combination with platinum and 5-fluorouracil chemotherapy, for 1st line treatment of metastatic or unresectable...

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Revised SPCs: Octasa (mesalazine) modified release tablets – all strengths

Remove: electronic Medicines Compendium - eMC source - 25 November 2019 - Publisher: electronic Medicines compendium

Nephrolithiasis (kidney stones) added as an undesirable effect of treatment with unknown frequency.

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Revised SPC: Darzalex (daratumumab) 20 mg/mL concentrate for solution for infusion

Remove: electronic Medicines Compendium - eMC source - 21 November 2019 - Publisher: electronic Medicines compendium

SPC updated to include a new licensed indication; as monotherapy for treatment of adult patients with relapsed and refractory multiple myeloma, whose prior therapy included a proteasome inhibitor and...

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Revised SPCs: Ibrance (palbociclib) hard capsules – all strengths

Remove: electronic Medicines Compendium - eMC source - 25 November 2019 - Publisher: electronic Medicines compendium

Interstitial lung disease and/or pneumonitis added as adverse effects of treatment based on pooled dataset from 3 randomised studies; together with relevant discontinuation recommendations. The...

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Revised SPC: CosmoFer (iron[III]-hydroxide dextran complex)

Remove: electronic Medicines Compendium - eMC source - 10 December 2019 - Publisher: electronic Medicines compendium

SPC now warns foetal bradycardia may occur following administration of parenteral irons, which is usually transient and consequence of hypersensitivity reaction in the mother. Unborn baby should be...

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Revised SPCs: Plavix (clopidogrel) 75 and 300 mg film-coated tablets

Remove: electronic Medicines Compendium - eMC source - 10 December 2019 - Publisher: electronic Medicines compendium

SPC now warns that as with other oral P2Y12 inhibitors, co-administration of opioid agonists has potential to delay and reduce absorption of clopidogrel, presumably because of slowed gastric...

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Revised SPC: Tenoretic and Tenoret (atenolol/chlortalidone) tablets

Remove: electronic Medicines Compendium - eMC source - 29 November 2019 - Publisher: electronic Medicines compendium

SPC’s have been updated to include a change in, the colour and description of the tablets, the excipients, and storage conditions.

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