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Results for all evidence | Drugs and Technologies | electronic Medicines Compendium - eMC | Medicines Current Awareness 31 - 40 of 260 sorted by relevance / date

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Revised SPC: Sivextro (tedizolid phosphate) 200 mg powder for concentrate for solution for infusion

Remove: electronic Medicines Compendium - eMC source - 22 January 2020 - Publisher: electronic Medicines compendium

SPC has been updated to provide clarification that when reconstituted/diluted, the solution should be stored between 2°C - 8°C when in a refrigerator.

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New product: Sunosi (solriamfetol) 75 and 150 mg film-coated tablets

Remove: electronic Medicines Compendium - eMC source - 22 January 2020 - Publisher: electronic Medicines compendium

Solriamfetol is licensed to improve wakefulness and reduce excessive daytime sleepiness (EDS) in adult patients with narcolepsy (with/without cataplexy) or with obstructive sleep apnoea (OSA), whose...

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Revised SPC: Bavencio (avelumab) 20 mg/mL concentrate for solution for infusion

Remove: electronic Medicines Compendium - eMC source - 01 November 2019 - Publisher: electronic Medicines compendium

SPC has been updated with additional information regarding the new licensed indication - in combination with axitinib, avelumab is licensed for the first-line treatment of adult patients with...

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Revised SPC: Tagrisso (osimertinib mesylate) tablets – all strengths

Remove: electronic Medicines Compendium - eMC source - 01 November 2019 - Publisher: electronic Medicines compendium

SPC notes that based on clinical studies and population pharmacokinetic analysis, no dose adjustments are necessary in patients with mild, moderate, or severe renal impairment. Safety and efficacy...

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Revised SPC: Extavia (interferon beta-1b) 250 microgram/ml powder and solvent for solution for injection

Remove: electronic Medicines Compendium - eMC source - 01 November 2019 - Publisher: electronic Medicines compendium

SPC has been updated with exposure data in pregnancy (>1,000 pregnancy outcomes) indicating that if clinically required, use of Extavia may be considered during pregnancy and breastfeeding.

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Revised SPC: Celebrex (celecoxib) 100mg capsule

Remove: electronic Medicines Compendium - eMC source - 13 January 2020 - Publisher: electronic Medicines compendium

Section 4.4 now includes concomitant use of antiplatelet drugs as a risk factor for increased incidence for upper and lower gastrointestinal complications.

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Revised SPC: Remicade (infliximab) 100mg powder for concentrate for solution for infusion

Remove: electronic Medicines Compendium - eMC source - 28 October 2019 - Publisher: electronic Medicines compendium

‘Cerebrovascular accidents in close temporal association with infusion’ has been added to SPC as adverse effect of unknown frequency.

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New product: Oncaspar (pegaspargase) 750 U/ml powder for solution for injection/infusion

Remove: electronic Medicines Compendium - eMC source - 28 October 2019 - Publisher: electronic Medicines compendium

Oncaspar is licensed as a component of antineoplastic combination therapy in acute lymphoblastic leukaemia in paediatric patients from birth to 18 years, and adult patients. It is already available...

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Revised SPC: Ketalar (ketamine) injection

Remove: electronic Medicines Compendium - eMC source - 02 January 2020 - Publisher: electronic Medicines compendium

SPC now states that long term use is not recommended owing to cases of cystitis, including haemorrhagic cystitis, acute kidney injury, hydronephrosis, and ureteral disorders that have been reported...

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Revised SPC: Opdivo (nivolumab) concentrate for solution for infusion

Remove: electronic Medicines Compendium - eMC source - 29 October 2019 - Publisher: electronic Medicines compendium

SPC has been updated to detail a change in dosing for the treatment of adjuvant melanoma. A flat dose of 240 mg every 2 weeks or 480 mg every 4 weeks is recommended instead of weight based dosing.

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