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Results for all evidence | Primary Research | NIHR Journals Library - Health Services and Delivery Research 1 - 10 of 371 sorted by relevance / date

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A Poisson approach to the validation of failure time surrogate endpoints in individual patient data meta-analyses.

Remove: PubMed source - 07 July 2017 - Publisher: Statistical methods in medical research.

AbstractSurrogate endpoints are often used in clinical trials instead of well-established hard endpoints for practical convenience. The meta-analytic...

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Evaluating progestogens for prevention of preterm birth international collaborative (EPPPIC) individual participant data (IPD) meta-analysis: protocol.

Remove: PubMed source - 01 December 2017 - Publisher: Systematic reviews.

AbstractBACKGROUND: Preterm birth is the most common cause of death and harm to newborn babies. Babies that are born early may have difficulties at...

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Resource implications of preparing individual participant data from a clinical trial to share with external researchers.

Remove: PubMed source - 18 July 2017 - Publisher: Trials.

AbstractBACKGROUND: Demands are increasingly being made for clinical trialists to actively share individual participant data (IPD) collected from...

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Practical implications of using real-world evidence (RWE) in comparative effectiveness research: learnings from IMI-GetReal.

Remove: PubMed source - 01 September 2017 - Publisher: Journal of comparative effectiveness research.

AbstractIn light of increasing attention towards the use of real-world evidence (RWE) in decision making in recent years, this commentary aims to...

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Combining randomized and non-randomized evidence in network meta-analysis.

Remove: PubMed source - 14 January 2017 - Publisher: Statistics in medicine.

AbstractNon-randomized studies aim to reveal whether or not interventions are effective in real-life clinical practice, and there is a growing...

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A comparison of bivariate, multivariate random-effects, and Poisson correlated gamma-frailty models to meta-analyze individual patient data of ordinal scale diagnostic tests.

Remove: PubMed source - 12 July 2017 - Publisher: Biometrical journal. Biometrische Zeitschrift.

AbstractIndividual patient data (IPD) meta-analyses are increasingly common in the literature. In the context of estimating the diagnostic accuracy of

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A closed testing procedure to select an appropriate method for updating prediction models.

Remove: PubMed source - 29 November 2016 - Publisher: Statistics in medicine.

AbstractPrediction models fitted with logistic regression often show poor performance when applied in populations other than the development...

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Explicit inclusion of treatment in prognostic modeling was recommended in observational and randomized settings.

Remove: PubMed source - 06 April 2016 - Publisher: Journal of clinical epidemiology.

AbstractOBJECTIVES: To compare different methods to handle treatment when developing a prognostic model that aims to produce accurate probabilities of

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Individual patient-versus literature-based meta-analysis of survival data: time to event and event rate at a particular time can make a difference, an example based on head and neck cancer.

Remove: PubMed source - 02 October 2001 - Publisher: Controlled clinical trials.

AbstractThe objective of this study is to compare the results of an individual patient-based and a literature-based meta-analysis in chemotherapy in...

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Estimating number of events from the Kaplan-Meier curve for incorporation in a literature-based meta-analysis: what you don't see you can't get!

Remove: PubMed source - 14 September 2000 - Publisher: Biometrics.

AbstractIn literature-based meta-analyses of time-to-event data, the number of events in the treated and control groups together with the total number

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